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Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote - US only)
Updated: Yesterday
Location: Remote, PR, United States
Job ID: 25111448-OTHLOC-1500-2DPR-2DR
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Description
Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote - US only)Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.
Discover what your 25,000 future colleagues already know:
Why Syneos Health
- We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
- We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
- We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.
Job Responsibilities
Global Trials Optimization Specialist
Sponsor Dedicated/ Remote - US only
Help Shape the Success of Global Clinical Trials
Are you energized by using data, strategic planning, and cross-functional collaboration to help clinical trials achieve enrollment success? We're seeking a Global Trials Optimization Specialist to support program feasibility, recruitment and retention strategy, and in-life trial optimization across global clinical studies within General Medicine, Dermatology, Rheumatology, Infectious Disease, and Vaccine programs.
In this role, you'll transform trial goals, country insights, enrollment analytics, and feasibility data into actionable strategies that drive study performance. Working closely with clinical trial teams, country stakeholders, vendors, legal partners, and analytics teams, you'll help identify enrollment opportunities, mitigate risks, and support effective patient and site engagement initiatives.
This is an outstanding opportunity for a clinical research professional who enjoys blending clinical operations, feasibility strategy, patient recruitment, stakeholder management, and data-driven decision-making to improve clinical trial outcomes on a global scale.
What You’ll Do
Program Feasibility and Trial Optimization
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Gather data, benchmarks, and modeling inputs to support feasibility and trial optimization planning.
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Support program review development, including content review and escalation of requirements as needed.
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Plan timelines for validation, deliverable development, stakeholder alignment, presentation preparation, and country validation requests.
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Support validation and Clinical Trials Allocation Committee activities, including scenario planning, risk table inputs, validation review, modeling updates, and final allocation requests.
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Author the initial Global Trials Optimization Report and maintain subsequent report updates throughout the trial lifecycle.
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Complete recruitment needs assessments and ensure trial-level GTO reports remain current and actionable.
Recruitment and Retention Planning
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Lead early recruitment and retention planning during feasibility, including inputs for project cost estimates.
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Develop initial recruitment needs assessments and, where applicable, program-level recruitment budget estimates.
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Submit vendor requests and prepare recruitment and retention plans.
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Partner with legal on concept reviews, vendor proposal reviews, scope of work finalization, and material or tactic reviews.
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Ensure recruitment and retention plans, including enrollment support materials, are implemented effectively.
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Oversee enrollment support material development and tactic execution.
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Provide required materials to the Metrics, Analytics & Performance team to support accurate Study Optimizer plan entry.
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Request and manage appropriate system updates as trial needs evolve.
In-Life Trial Management
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Partner with study teams to identify enrollment challenges, assess risks, and recommend potential mitigations.
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Manage routine enrollment support materials and vendor activities.
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Monitor enrollment performance and prepare standard reporting.
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Analyze performance trends and identify opportunities for enhanced support.
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Coordinate enhanced enrollment support activities, which may include:
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Rescue site and country activities
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Internal recruitment and retention refresher meetings
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External recruitment and retention booster meetings
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Additional participant- or site-facing materials
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Rescue vendor engagement
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Advocacy engagement and community outreach
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What You’ll Bring
Required Qualifications
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Experience supporting clinical trials, feasibility assessments, recruitment planning, enrollment strategy, trial optimization, or related clinical operations activities.
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Strong analytical skills with the ability to collect, interpret, and apply data to support decision-making.
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Experience managing timelines, deliverables, stakeholder reviews, and cross-functional initiatives.
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Ability to collaborate effectively with study teams, vendors, legal partners, analytics groups, and operational stakeholders.
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Excellent written and verbal communication skills, including the ability to develop reports, recommendations, presentations, and strategic plans.
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Strong organizational skills and attention to detail in a fast-paced clinical research environment.
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Ability to manage multiple studies and competing priorities while maintaining quality and accuracy.
Highly Preferred Qualifications
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Experience supporting clinical trials within General Medicine, Dermatology, Rheumatology, Infectious Disease, or Vaccine therapeutic areas.
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Prior experience as a Clinical Research Coordinator, Site Coordinator, Clinical Trial Associate, or similar site-based research role.
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Experience with patient recruitment and retention vendors and enrollment support campaigns.
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Familiarity with patient engagement strategies and patient-centered trial approaches.
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Experience developing patient-facing or site-facing recruitment materials.
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Knowledge of enrollment forecasting, country validation processes, risk assessments, feasibility methodologies, or trial allocation strategies.
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Experience monitoring and analyzing enrollment performance metrics to drive operational improvements.
Why This Role Matters
Successful clinical trials depend on identifying the right sites, reaching the right participants, and adapting quickly when enrollment challenges arise. As a Global Trials Optimization Specialist, you'll play a critical role in helping studies achieve enrollment goals through thoughtful planning, innovative recruitment strategies, and data-driven optimization.
Your contributions will directly support global trial success by:
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Improving study feasibility planning.
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Enhancing patient recruitment and retention outcomes.
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Supporting sites with effective enrollment strategies.
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Providing actionable insights that drive operational decisions.
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Helping bring innovative therapies and vaccines to patients more efficiently.
You'll have the opportunity to collaborate with experienced clinical research professionals across functions and geographies while contributing to meaningful clinical research programs that impact patient lives worldwide.
Candidate Profile
We're especially interested in candidates who bring experience across General Medicine, Dermatology, Rheumatology, Infectious Disease, and Vaccine studies, along with a strong understanding of clinical trial operations, site engagement, enrollment strategy, and recruitment and retention planning.
Successful candidates are:
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Strategic thinkers who use data to drive decisions.
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Strong collaborators who build productive cross-functional relationships.
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Organized project managers who thrive in dynamic environments.
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Problem-solvers who proactively identify enrollment risks and opportunities.
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Passionate clinical research professionals committed to improving trial execution and patient access.
If you're a clinical research professional who enjoys bringing insight, structure, and strategy to global trial enrollment and optimization efforts, we'd love to hear from you. Apply today and help drive the success of meaningful clinical research programs around the world.
Salary range for this role is $95,000–$105,000
At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.
Salary Range:
$80,600.00 - $145,000.00The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.
Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
Additional Information
Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
Summary
Under the direction of a Project Manager Lead supports overall project management of clinical studies by helping control the scope, schedule and cost of assigned project(s), which may range from single service studies to full scope or multiple protocol projects. Duties may include liaising with Customers, vendors and/or investigative sites to manage projects from proposal development to final deliverables to the customer. Upon displaying proficiency, a Project Manager (PM I) may be awarded the opportunity to function at the Project Manager II (PM II) level within a large project team or on a small project which offers continued mentorship.